Correlation of Serum Cholesterol and S.C.B.R. in Control study of Essential Hypertension Patient

Abstract

Introduction:
Arteriosclerosis, a Genetic term for Thickening and Hardening of the Arterial Wall is now responsible for the Majority of Deaths. Arthrosclerosis”
was First Introduced by Marchand In 1904. Atherosclerosis may be Accelerated by a Decreased Clearance of Cholesterol from Arterial Wall
Secondary to a Reduction of Plasma Concentration of H.D.L. In Atherosclerotic Lesion, the Lipid Content of Elastin increases Progressively with
increasing Severity of Atherosclerosis. The Increases in the Lipid Content of Plaque Elastin are Mainly due to large increases in Cholesterol.
Aim: Correlation of Serum Cholesterol and S.C.B.R. in Control study of Essential Hypertension.
Inclusion Criteria:25 patients of essential hypertension.
Exclusion Criteria: Nonsmokers and Secondary Hypertension.
Methodology: Obtain Serum specimen in usual way, alternatively EDTA plasma may also be used as specimen. The sample should preferable be
12- 14 hours fasting and using the principle of Serum Cholesterol and SCBR, readings has come out, the readings are further calculated.
Result: Mean S.C.B.R. was 59.719+6.99 mg% and mean serum cholesterol was 186.8+32.009 mg% in 25 controls. Correlation coefcient
between serum cholesterol and S.C.B.R. was +0.706 (p <0.001), denoting that S.C.B.R. rises with increasing level of cholesterol in control.
Conclusion: The study shows signicance coo-relation between Serum cholesterol and S.B.C.R