HISTOPATHOLOGICAL STUDY OF TUMOURS OF CERVIX

Abstract

Carcinoma of cervix is the most common cancer in Indian women and accounts for 20% of all malignant tumours in the females. Squamous cell carcinomas (SCC) account for 75-80%, adenocarcinoma 15-25%, and adenosquamous carcinomas 3-5% of cervical cancers. Objectives: To study histopathology of carcinoma of cervix and to find out the incidence rate, most common type of the carcinoma of cervix and to find out age predilection in various types of carcinoma of cervix. Material and Method: This study was undertaken in the department of pathology over a period of 2 years from May 2010 to April 2012. All Hysterectomy specimens and cervical biopsies were rocessed routinely and paraffin sections were taken and stained with Haematoxylin and Eosin (H&E) for microscopic examination. Tumours of the cervix were classified and studied according to WHO classification. Results: The most frequent condition diagnosed on cervical biopsies and hysterectomy specimens were benign cervical polyp (66.3%), followed by carcinoma (23.7%) and squamous intraepithelial lesion (0.2%). Out of all benign cervical polyps, occurrence of adenomatous polyp  was highest. Incidence of squamous cell carcinoma (19.6%) was more as compared to adenocarcinoma (3.7%). The mean age of the squamous cell carcinoma, adenocarcinoma, squamous intraepithelial lesion and benign cervical polyp was 49.1 years, 43.5 years, 47.7 years and 44.6 years respectively. Conclusion: Incidence of squamous cell carcinoma was more as compared to adenocarcinoma. Occurrence of malignant lesions was earlier during 4 th decade as compared to benign cervical lesions