Trends of Organisms and Their Antibiotic Sensitivity in NICU

Abstract

Aim and Objective: To assess the pattern of bacterial isolates in our NICU along with their antibiotic sensitivity pattern so that guidelines could be prepared for a rational antibiotic therapy. Study Design: A retrospective hospital based study. Place and Duration Of Study: NICU of Sangameshwar hospital, Gulbarga from Nov 2012 to Aug 2013. Material and Methods: All neonates admitted in our NICU with positive culture were included in this study. Culture reports were analyzed for bacterial isolates along with their antibiotic sensitivity pattern. Results: 139 organisms were isolated from the 442 cultures. Staphylococcus aureus was the main pathogen during this period. Resistance to methicillin is 18%. Among gram negative organisms, klebsiella is most common. Conclusion: Staphylococcus aureus is the most common organism. Meropenam is the most sensitive drug for gram negative organisms, vancomycin followed by linezolid for gram positive organisms. These drugs should be used as second line drugs otherwise resistance increases over tim