A Clinical Study of Treatment Outcomes in Patients with Liver Abscess in a Tertiary Care Hospital

Abstract

 Introduction: This study investigated treatment outcomes in 200 patients with liver abscesses over 1.5 years at a tertiary care hospital.

Materials & Methods: Patient demographics, clinical presentations, treatment methods, and outcomes such as abscess resolution, complications, and hospital stay duration were examined.

Results: Results revealed that antibiotic therapy alone was successful in 72% of cases, particularly for abscesses smaller than 5 cm and in patients who were hemodynamically stable. Percutaneous drainage was employed in 20% of patients, demonstrating a high success rate with minimal complications, and was most effective for abscesses that were not amenable to antibiotic treatment alone. Surgical intervention was required in 8% of cases, especially for large or multi-loculated abscesses, or those with complications like rupture or sepsis, resulting in longer hospital stays and a higher complication rate compared to less invasive treatments. Factors influencing outcomes included abscess size, patient comorbidities, and initial response to antibiotics.

Conclusion: The study underscores the significance of early diagnosis and individualized treatment plans in achieving favorable outcomes for patients with liver abscesses. A multidisciplinary approach is recommended for managing complex cases to optimize patient outcomes and minimize complications. The study suggests the need for further prospective research to refine treatment strategies and improve patient care in liver abscess management.